Researchers Identifies New Genetic Variants for Lung Cancer Risk

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Largest genome-wide study of lung cancer susceptibility conducted.
Image source: Live Science
A new study conducted by an international team of lung cancer researchers, including Professor John Field from the University of Liverpool, have identified new genetic variants for lung cancer risk....


Genotyping is the process of determining differences in the genetic make-up (genotype) of an individual by examining the individual's DNA sequence.


Researchers examined the data to identify the genetic variants associated with lung cancer risk.

During the study, published in Nature Genetics, more than 29,200 lung cancer cases and more than 56,000 samples taken from people without lung cancer (controls) were examined. Researchers identified 18 genetic variations that could make people more susceptible to lung cancer and also 10 new gene variations.


"This study has identified several new variants for lung cancer risk that will translate into improved understanding of the mechanisms involved in lung cancer risk...."These results will help us to further improve the way we can screen for lung cancer in high risk individuals in the UK. Further studies will help in the targeting of specific genes to influencing lung cancer risk, smoking behaviour and smoking effects on brain biology."


"This study definitely leads to new ideas about mechanisms influencing lung cancer risk."


Read Full Post: Largest Genome-Wide Study Of Lung Cancer Susceptibility Conducted

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